Centralt kæmpegranulom (CGCG) er en sjældent forekommende, benign, destruktiv læsion i kæberne, som af WHO karakteriseres ved en uindkapslet spredning af mononukleære spindelformede og polygonale celler med tilstedeværelsen af osteoklastlignende, multinukleære kæmpeceller i en vaskulær baggrund. CGCG udgør ca. 7 % af alle benigne, tumorøse læsioner i kæberne
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