Organ transplant patients are a growing group of medically compromised patients who must receive life-long immunosuppressant treatment. However, the prognosis for these patients is excellent. For example, 5-year survival of liver transplant patients is 85 % and their quality of life corresponds to that of the normal population. From the standpoint of dental health, it is essential to diagnose and properly treat all potential oral and dental infections in order to avoid systemic complications. Dental treatment of organ transplant patients often calls for hospital dentistry, and special treatment units need to be consulted. Maintaining good oral hygiene daily is extremely important for these patients.