The increased risk of periodontal and peri-implant inflammation and impaired tissue healing in patients with hyperglycemia are among the issues elaborated in this review, in addition to discussing the biological background.

As many as one in every five children has a chronic systemic illness, the most prevalent being allergies, asthma, diabetes and autoimmune diseases, of which rheumatoid arthritis is the most common.

A possible mutual effect of treatment is not ascertained. For future studies, it may be valuable to examine subgroups of RA patients, paying more attention to medication and confounders.